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Coronary microvascular density (MVD) and fibrosis in HFpEF and HFrEF. Microvascular Density (MVD, A) and percent fibrosis (B) are compared among controls (n=104), HFpEF (n=124) and HFrEF (n=27) patients. Data are displayed as Tukey box plots. In C, log-transformed % fibrosis increases with decreasing MVD but remains higher in HFrEF than control. In HF patients, adjusting for MVD, fibrosis is similar in HFpEF and HFpEF.
