Table 1.
Anthropometric and metabolic parameters of Latino adolescents (n=164) 2-way ANOVA; #sample size =55
| NGT (n=107) | Pre-diabetes (n=57) | P-value | |
|---|---|---|---|
| Age (years) | 14.3 ± 2.4 | 14.0 ± 2.6 | 0.532 |
| Sex (Male/Female) | 62/45 | 33/24 | |
| Tanner Stage | |||
| 2 | 27 | 20 | |
| 3 | 12 | 9 | |
| 4 | 20 | 8 | |
| 5 | 48 | 20 | |
| Weight (kg) | 78.3 ± 20.0 | 83.0 ± 23.8 | 0.186 |
| Height (cm) | 160.5 ± 11.6 | 159.4 ± 12.4 | 0.563 |
| BMI (kg/m2) | 30.1 ± 5.8 | 32.3 ± 6.8 | 0.030 |
| BMI z-score | 1.9 ± 0.5 | 2.1 ± 0.5 | 0.017 |
| Total Fat mass (kg) | 29.2 ± 1.0 | 30.6 ± 1.1 | 0.401 |
| Total Lean mass (kg) | 45.7 ± 1.2 | 47.6 ± 1.3 | 0.340 |
| Total % Fat | 37.5 ± 6.7 | 38.0 ± 7.2 | 0.672 |
| Visceral Adipose Tissue (L) | 1.6 ± 1.0 | 1.9 ± 1.2 | 0.137 |
| Subcutaneous Abdominal Adipose Tissue (L) | 6.5 ± 3.3 | 7.2 ± 3.9 | 0.193 |
| Fasting Glucose (mg/dL) | 86.7 ± 5.6 | 90.2 ± 7.7 | 0.003 |
| 2-hr Glucose (mg/dL) | 115.2 ± 15.1 | 138.6 ± 23.3 | <0.001 |
| HbA1c (%) | 5.5 ± 0.3 | 5.9 ± 0.3 | <0.001 |
| HbA1c (mmol/mol) | <0.001 | ||
| Fasting Insulin (μU/mL) | 13.1 ± 8.9 | 16.0 ± 11.3 | 0.091 |
| Insulin AUCOGTT (μU/mL x min) | 175.1 ± 110.0 | 229.1 ± 163.8 | 0.029 |
| Insulin AUCNOCTURNAL (μU/mL x min) | 52.4 ± 26.0 | 71.7 ± 39.0 | 0.040 |
| Fasting FFA (mmol/L) | 0.68 ± 0.14 | 0.73 ± 0.14 | 0.032 |
| FFA AUCOGTT (mmol/L x min) | 0.61 ± 0.13 | 0.66 ± 0.13 | 0.045 |
| FFA AUCNOCTURNAL (mmol/L x min) | 1.56 ± 0.36 | 1.51 ± 0.28 | 0.542 |
| Insulin sensitivity [(x10−4 min−1)/(μU/mL)] | 2.02 ± 1.19 | 1.45 ± 0.86 | 0.001 |
| Acute Insulin Response (μU/mL x 10min) | 1302 ± 853 | 1448 ± 987 | 0.351 |
| Disposition index | 2188 ± 1087 | 1735 ± 1035 | 0.041 |