Table 2.
Observed unadjusted rates of intraoperative and postoperative outcomes
| Outcome | Total
|
Neoadjuvant patients
|
Surgery-only patients
|
P |
|---|---|---|---|---|
| n = 1939 | n = 708 (36.5%) | n = 1231 (63.5%) | ||
| 30-day mortality (%) | 70 (3.6) | 21 (3.0) | 49 (4.0) | 0.249 |
| Overall morbidity† (%) | 956 (49.3) | 343 (48.5) | 613 (49.8) | 0.567 |
| Wound infection | 265 (13.7) | 100 (14.1) | 165 (13.4) | 0.657 |
| Pneumonia | 303 (15.6) | 90 (12.7) | 213 (17.3) | 0.007 |
| Urinary tract infection | 68 (3.5) | 18 (2.5) | 50 (4.1) | 0.080 |
| Return to OR | 240 (12.4) | 197 (13.7) | 143 (11.6) | 0.180 |
| Venous thromboembolism | 122 (6.3) | 55 (7.8) | 67 (5.4) | 0.042 |
| Cardiac complication | 57 (2.9) | 17 (2.4) | 40 (3.3) | 0.287 |
| Shock/sepsis | 361 (18.6) | 117 (16.5) | 244 (19.8) | 0.073 |
| Unplanned intubation | 266 (13.7) | 89 (12.6) | 177 (14.4) | 0.265 |
| Bleeding transfusion | 158 (8.2) | 76 (10.7) | 82 (6.7) | 0.002 |
| Renal complication | 39 (1.93) | 10 (1.36) | 29 (2.27) | 0.151 |
| On ventilator >48 hours | 293 (15.1) | 96 (13.6) | 197 (16.0) | 0.148 |
| Organ space SSI | 113 (5.8) | 40 (5.7) | 73 (5.9) | 0.800 |
| Serious morbidity‡ (%) | 651 (33.6) | 223 (31.5) | 428 (34.8) | 0.142 |
| Length of stay, days (median) | 15.8 ± 21.0 (11) | 15.2 ± 14.4 (11) | 16.2 ± 24.0 (12) | 0.279 |
| Prolonged length of stay (%) | 512 (26.4) | 173 (24.4) | 339 (27.5) | 0.136 |
| Operative time, minute (median) | 340.4 ± 124.7 (325) | 344.3 ± 122.3 (325) | 338.1 ± 126.0 (324) | 0.290 |
| Prolonged operative time (%) | 485 (25.0) | 175 (24.7) | 310 (25.2) | 0.820 |
†
Overall morbidity: wound infection, pneumonia, urinary tract infection, venous thromboembolism, bleeding transfusion, renal complication, return to OR, cardiac complication, shock/sepsis, unplanned intubation, on ventilator >48 hours, and organ space SSI.
‡
Serious morbidity: return to OR, cardiac complication, shock/sepsis, unplanned intubation, on ventilator >48 hours, and organ space SSI. Bold indicates statistically significant values. OR, operative room; SSI, surgical site infection.