Table 4.
Observed unadjusted rates of intraoperative and postoperative outcomes in the matched cohort
| Outcome | Total
|
Neoadjuvant patients
|
Surgery-only patients
|
P |
|---|---|---|---|---|
| n = 990 | n = 495 | n = 495 | ||
| 30-day mortality (%) | 39 (3.9) | 18 (3.6) | 21 (4.2) | 0.624 |
| Overall morbidity† (%) | 487 (49.2) | 242 (48.9) | 245 (49.5) | 0.849 |
| Wound infection | 134 (13.5) | 72 (14.6) | 62 (12.5) | 0.353 |
| Pneumonia | 146 (14.8) | 64 (12.9) | 82 (16.6) | 0.107 |
| Urinary tract infection | 33 (3.3) | 12 (2.4) | 21 (4.2) | 0.111 |
| Return to OR | 123 (12.4) | 66 (13.3) | 57 (11.5) | 0.386 |
| Venous thromboembolism | 72 (7.3) | 46 (9.3) | 26 (5.3) | 0.014 |
| Cardiac complication | 24 (2.4) | 10 (2.0) | 14 (2.8) | 0.408 |
| Shock/sepsis | 176 (17.8) | 84 (17.0) | 92 (18.6) | 0.506 |
| Unplanned intubation | 130 (13.1) | 64 (12.9) | 66 (13.3) | 0.851 |
| Bleeding transfusion | 85 (8.6) | 43 (8.7) | 42 (8.5) | 0.910 |
| Renal complication | 14 (1.4) | 5 (1.0) | 9 (1.8) | 0.282 |
| On ventilator >48 hours | 148 (15.0) | 72 (14.5) | 76 (15.4) | 0.721 |
| Organ space SSI | 53 (5.4) | 28 (5.7) | 25 (5.1) | 0.672 |
| Serious morbidity‡ (%) | 324 (32.7) | 156 (31.5) | 168 (33.9) | 0.416 |
| Length of stay, days (median) | 16.0 ± 26.8 (11) | 14.8 ± 14.6 (10) | 17.1 ± 34.8 (12) | 0.190 |
| Prolonged length of stay (%) | 250 (25.3) | 112 (22.6) | 138 (27.9) | 0.057 |
| Operative time, minute (median) | 341.3 ± 126.1 (326) | 342.2 ± 122.2 (324) | 340.5 ± 130.1 (328) | 0.832 |
| Prolonged operative time (%) | 246 (24.9) | 120 (24.2) | 126 (25.5) | 0.659 |
†
Overall morbidity: wound infection, pneumonia, urinary tract infection, venous thromboembolism, bleeding transfusion, renal complication, return to OR, cardiac complication, shock/sepsis, unplanned intubation, on ventilator >48 hours, and organ space SSI.
‡
Serious morbidity: return to OR, cardiac complication, shock/sepsis, unplanned intubation, on ventilator >48 hours, and organ space SSI. Bold indicates statistically significant values. OR, operative room; SSI, surgical site infection.