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. 2015 Jan 16;13:8. doi: 10.1186/s12967-014-0369-9

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© Kumar et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Immunohistochemical analysis of S100A2 in oral tissues. Paraffin-embedded sections of histologically normal mucosa and OSCC were stained using a rabbit monoclonal anti-S100A2 antibody (0.5 μg/ml, [EPR5392] (ab109494, Abcam, CA) as described in Material & Methods section. Panel represents (a) normal oral mucosa showing nuclear S100A2 immunostaining; (b) OSCC section illustrating cytoplasmic S100A2 and loss of nuclear staining in tumor cells; (c) Cervical cancer tissue section showing cytoplasmic S100A2 immunostaining; (d) OSCC section used as a negative control, showing no S100A2 immunostaining in tumor cells; (original magnification x 200).