Table 2.
Sleep Characteristics, Respiratory Events, Periodic Limb Movements of Sleep, and Serum Laboratory Findings (N = 12)
| Sleep Variable | Expected | Prechemotherapy Cycle 2
|
Post-Chemotherapy Cycle 2
|
||
|---|---|---|---|---|---|
| X̄ | SD | X̄ | SD | ||
| Sleep onset latency (minutes) | Less than 30 | 22.79 | 42.48 | 12.92 | 10.51 |
| Time in bed (minutes) (n = 9) | – | 495.13 | 32.71 | 502.38 | 34.76 |
| Total sleep time (minutes) | 420–540 | 360.04 | 89.78 | 395.58 | 41.44 |
| Total wake time (minutes) | Less than 30 | 118.6 | 60.99 | 97.53 | 39.09 |
| Sleep efficiency (%) | Greater than 85 | 74.2 | 15.12 | 80.19 | 7.1 |
| NREM stage 1 sleep (minutes) | – | 85.67 | 34.44 | 115.79 | 42.16 |
| NREM stage 2 sleep (minutes) | 210–324 | 199.5 | 77.69 | 204.92 | 40.58 |
| NREM stage 3–4 sleep (minutes) | 42–108 | 26.88 | 16.25 | 33.67 | 26.08 |
| REM sleep (minutes) | 84–135 | 48 | 19.82 | 41.21 | 32.23 |
| Total awakening indexa | Less than 6 | 4.78 | 4.65 | 4.96 | 2.14 |
| Apnea hypopnea indexb | – | 9.94 | 14.15 | 10.29 | 10.6 |
| Total SpO2 nadir (%) | Greater than 95 | 85.5 | 5.6 | 84.75 | 4.56 |
| PLMs total indexc | – | 8.01 | 11.68 | 16.01 | 17.11 |
| Serum creatinine (mg/dl) | 0.5–1.1 | 0.96 | 0.2 | 0.97 | 0.17 |
| Serum hemoglobin (g/dl) (n = 11) |
Male: 13.5–17.5 Female: 11.5–16 |
11.03 | 1.14 | 12.05 | 1.95 |
a
Per hour of sleep
b
Mild—less than 15; moderate—15–30; severe—greater than 30
c
Normal—less than 5; mild—5–24; moderate—25–50; severe—greater than 50
NREM—non–rapid eye movement; REM—rapid eye movement; PLMs—period limb movements; SpO2—hemoglobin oxygen concentration measured by pulse oximetry