Table 2.
Validation with SVM for the 16 pathway-based biomarkers.
| PATHWAY ID | TRAINING SET | TESTING SET | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PRECISION (%) | ACCURACY (%) | SENSITIVITY (%) | SPECIFICITY (%) | ROC (%) | PRECISION (%) | ACCURACY (%) | SENSITIVITY (%) | SPECIFICITY (%) | ROC (%) | |
| h_classicPathway | 80.56 | 77.50 | 72.50 | 82.50 | 87.88 | 71.43 | 72.50 | 75.00 | 70.00 | 78.63 |
| 500792 | 79.49 | 78.75 | 77.50 | 80.00 | 90.63 | 74.47 | 78.75 | 87.50 | 70.00 | 89.00 |
| hsa05322 | 73.17 | 73.75 | 75.00 | 72.50 | 88.88 | 69.39 | 73.75 | 85.00 | 62.50 | 82.19 |
| 166663 | 77.27 | 80.00 | 85.00 | 75.00 | 88.94 | 69.39 | 73.75 | 85.00 | 62.50 | 77.81 |
| h_lectinPathway | 73.91 | 77.50 | 85.00 | 70.00 | 89.56 | 64.29 | 65.00 | 67.50 | 62.50 | 75.63 |
| h_compPathway | 80.00 | 80.00 | 80.00 | 80.00 | 90.44 | 70.45 | 72.50 | 77.50 | 67.50 | 79.19 |
| 200149 | 72.22 | 70.00 | 65.00 | 75.00 | 78.69 | 57.14 | 53.75 | 30.00 | 77.50 | 65.19 |
| hsa04610 | 86.67 | 91.25 | 97.50 | 85.00 | 96.94 | 79.59 | 86.25 | 97.50 | 75.00 | 88.81 |
| 375276 | 80.56 | 77.50 | 72.50 | 82.50 | 89.69 | 75.56 | 78.75 | 85.00 | 72.50 | 86.75 |
| 373076 | 80.56 | 77.50 | 72.50 | 82.50 | 89.69 | 75.56 | 78.75 | 85.00 | 72.50 | 86.75 |
| 392499 | 82.05 | 81.25 | 80.00 | 82.50 | 93.25 | 78.26 | 82.50 | 90.00 | 75.00 | 91.88 |
| 381150 | 81.40 | 83.75 | 87.50 | 80.00 | 93.44 | 76.47 | 83.75 | 97.50 | 70.00 | 88.38 |
| 388396 | 92.50 | 92.50 | 92.50 | 92.50 | 98.19 | 82.98 | 88.75 | 97.50 | 80.00 | 94.81 |
| hsa05133 | 81.58 | 80.00 | 77.50 | 82.50 | 90.94 | 73.81 | 75.00 | 77.50 | 72.50 | 81.44 |
| hsa05150 | 84.09 | 87.50 | 92.50 | 82.50 | 93.81 | 73.91 | 77.50 | 85.00 | 70.00 | 81.88 |
| 418594 | 86.11 | 82.50 | 77.50 | 87.50 | 91.13 | 80.00 | 83.75 | 90.00 | 77.50 | 87.75 |
| Mean | 80.76 | 80.70 | 80.63 | 80.78 | 90.75 | 73.29 | 76.56 | 82.03 | 71.09 | 83.50 |