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. Author manuscript; available in PMC: 2015 Feb 11.
Published in final edited form as: Am J Kidney Dis. 2011 Nov 9;59(1):152–159. doi: 10.1053/j.ajkd.2011.08.035

Figure 2.

Figure 2

Overview of FGF23 physiology

(+) corresponding to a positive effect

(−) corresponding to an inhibitory effect DMP1: dental matrix protein 1

FGF23: fibroblast growth factor 23

FGFR1: fibroblast growth factor receptor type 1

PHEX: phosphate-regulating gene with homologies to endopeptidases on X chromosome

PTH: parathyroid hormone

Npt 2: type II sodium-phosphate cotransporters (type a and c)