Overview of FGF23 physiology
(+) corresponding to a positive effect
(−) corresponding to an inhibitory effect DMP1: dental matrix protein 1
FGF23: fibroblast growth factor 23
FGFR1: fibroblast growth factor receptor type 1
PHEX: phosphate-regulating gene with homologies to endopeptidases on X chromosome
PTH: parathyroid hormone
Npt 2: type II sodium-phosphate cotransporters (type a and c)