Figure 2. Measuring FMD, LFMC and Shear Rate AUC.
This figure illustrates the three components of the FMD test – FMD, LFMC and shear rate AUC. Diameter and velocity are measured continuously throughout the test. FMD and LFMC may be calculated as an absolute or a percent change in artery diameter. FMD is calculated as the change in diameter from baseline, to the maximum diameter reached after cuff release. LFMC is the change in diameter from baseline to the end of cuff inflation. Shear rate is calculated as blood flow velocity/diameter. Shear rate AUC is the area under the curve from the time of peak diameter, to the time of cuff release. Only increases in shear rate above baseline values are included.