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The medical therapies shown in the figure can be exerted at the pituitary, adrenal gland, or by blocking the binding of cortisol to the glucocorticoid receptor in the target tissue. ACTH, adrenocorticotropic hormone; DA, dopamine agonist; GR, glucocorticoid receptor; GRE, glucocorticoid response elements; SRL, somatostatin receptor ligand. Reproduced with permission from Fleseriu (2012).
