Figure 4. Contractile responses of rat thoracic aortic rings after photolysis of various analogues.

Isometric aortic tension recording was obtained with a curvilinear pen recorder after a 15 min incubation in the presence of caged analogues (10⁻⁸ m) followed by in situ photolysis with 30-W UV-lamp. A, control. B, [Tyr(DMNB)⁴]Ang-II. C, Ang-II-ODMNB. D, [Tyr(DMNB)⁴]Ang-II-DMNB. E, overall results as a percentage of contractile response induced by 40 mm KCl. Data are shown as the mean ± sem (n = 4 independent preparations from each of 4 animals per group).