Figure 2. Using the ‘T_env clamp’ method the duration that animals could withstand core temperature elevations above 40°C and the duration of the total heating and recovery period were significantly elevated in IL-6-treated animals.

Values are means ± SEM. Significance was determined by a two-sample t-test. Results are only from animals that survived the protocol: 60% in untreated HS, 63% in IL-6-treated HS.