Table 4.
Response and Survival by Grade 3–4 Anemia
| Stage | Grade 3–4 Anemia | No. | % MCyR | % CCyR | EFS, % at 7 Years (95% CI) | OS, % at 7 Years (95% CI) |
|---|---|---|---|---|---|---|
| ECP | Yes | 32 | 81 | 81 | 80 (66–94) | 90 (79–100) |
| No | 275 | 93a | 87a | 72 (66–78) | 88 (83–93) | |
| P | .03 | .37 | .91 | .56 | ||
| LCP | Yes | 30 | 53 | 40 | 25 (8–42) | 55 (37–74) |
| No | 271 | 80b | 75b | 65 (59–71) | 82 (77–86) | |
| P | .0007 | .0001 | .00006 | .001 |
MCyR indicates major cytogenetic response; CCyR, complete cytogenetic response; EFS, event-free survival; CI, confidence interval; ECP, early chronic phase; LCP, late chronic phase.
From 269 evaluable patients.
From 266 evaluable patients.