Fig. 6.
Human A30P α-syn overexpression increases GFAP-expressing astrocytes, which is suppressed by dox. Double-fluorescence confocal photomicrographs showed hypertrophic astrocytes immunostained with GFAP associated with overexpression of A30P but without col-localizing with human α-syn (B,C and inset) when compared to dox-treated (D) or crl (A). (E) Cell bodies and processes were quantified as total number and area fraction per 10 sight-fields and data are present as mean + SEM. *p < 0.05, **p < 0.01 versus ctl; Scale bar: 25 µm and 10 µm in insets.