Table 4.
Association of R990G:A986S haplotype with plasma iPTH, serum calcium, and serum 25OHD levels.
| R990G:A986S | Frequency | Mean plasma iPTH difference pg/mL (95% CI) |
P value | Mean serum calcium difference mg/dL (95% CI) |
P value | Mean serum 25OHD difference (95% CI) | P value |
|---|---|---|---|---|---|---|---|
| A:G | 0.68 | 0.00 | — | 0.00 | — | 0.00 | — |
|
| |||||||
| A:T | 0.17 | 15.3 (−7.06–37.64) |
0.18 | 0.1 (−0.07–0.26) |
0.25 | −1.5 (−3.8–0.77) |
0.2 |
|
| |||||||
| G:G | 0.12 | 49.4 (11.57–61.83) |
0.0049 | −0.11 (−0.29–0.08) |
0.26 | −0.9 (−3.63–1.69) |
0.48 |
|
| |||||||
| G:T | 0.03 | 36.7 (0.48–98.4) |
0.05 | −0.51 (−0.88–−0.14) |
0.0079 | −1.6 (−7.24–3.96) |
0.57 |
Haplotype association with quantitative variables was computed using online SNPstats software taking A:G haplotype as a reference.
P value < 0.05 was considered statistically significant.