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Representative sections from atria and the ventricles of one-month (1M) and six-month (6M) old TG mice stained with H&E (A and B) and trichrome (C and D). Fibrotic scar formation, collagen accumulation, myolysis and muscle disarray are progressive and are more prominent in 6M old TG mice hearts. Bar represents 50μm. Quantitation of fibrotic area in atria and in the ventricles are shown in panel E and F respectively.
