Table 2.
Variables | In-field control | Locoregional control | Freedom from distant metastasis | Freedom from progression | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
P value | HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | |
Attachment status: broad attachment vs. others | <0.01* | 11.5 | 2.42-81.5 | <0.01* | 4.60 | 1.91-10.8 | 0.01* | 3.02 | 1.22-7.19 | <0.01* | 3.78 | 1.87-7.40 |
Gender: female vs. male | 0.89 | 1.11 | 0.15-5.20 | 0.29 | 0.57 | 0.16-1.54 | 0.57 | 1.29 | 0.49-3.03 | 0.54 | 0.79 | 0.35-1.62 |
Diagnosis: pathological vs. clinical | 0.17 | 3.59 | 0.60-68.1 | 0.15 | 2.00 | 0.78-6.13 | 0.19 | 1.81 | 0.75-5.09 | 0.11 | 1.79 | 0.87-4.04 |
Tumor diameter (cm): per 1 cm increase | <0.01* | 3.71 | 1.47-9.72 | <0.01* | 2.25 | 1.30-3.83 | <0.01* | 2.01 | 1.19-3.33 | <0.01* | 2.02 | 1.32-3.07 |
Perfomance status: 0-1 vs. 2-3 | 0.97 | 0.96 | 0.15-18.5 | 0.88 | 1.09 | 0.36-4.71 | 0.38 | 1.81 | 0.52-11.3 | 0.48 | 1.42 | 0.56-4.81 |
SBRT dose (BED10): > 102 Gy10 vs. ≤ 102 Gy10 | 0.02* | 0.13 | 0.01-0.79 | 0.59 | 1.25 | 0.54-3.05 | 0.88 | 0.94 | 0.45-2.02 | 0.77 | 0.90 | 0.47-1.75 |
Prescription: isocenter vs. D95 | 0.53 | 1.88 | 0.30-36.3 | 0.94 | 0.96 | 0.35-3.01 | 0.79 | 0.88 | 0.35-2.48 | 0.27 | 0.64 | 0.30-1.45 |
Attachment status: broad attachment vs. others | 0.15 | 4.00 | 0.59-35.6 | 0.02* | 3.08 | 1.15-8.27 | 0.19 | 1.93 | 0.70-5.29 | 0.01* | 2.66 | 1.21-5.73 |
Tumor diameter (cm): per 1 cm increase | 0.04* | 3.65 | 1.00-14.1 | 0.12 | 1.67 | 0.86-3.10 | 0.09 | 1.68 | 0.91-3.00 | 0.06 | 1.59 | 0.96-2.55 |
SBRT dose (BED10): > 102 Gy10 vs. ≤ 102 Gy10 | 0.02* | 0.10 | 0.01-0.75 | n.s. | n.s. | n.s |
Abbreviations: D95, doses covering 95% of the planning target volume; BED, biological effective dose; HR, hazard ratio; CI, confidence interval; n.s, not significant. *p < 0.05.