Table 1.
Characteristics at study enrolment of all 32 patients with non-CF bronchiectasis and of the subset of 22 who experienced exacerbations during the study period
| Whole cohort (n = 32) | Patients experiencing exacerbations during study period (n = 22) | |
|---|---|---|
| Age (years), mean (SD) | 61 (12) | 59 (12) |
| Female patients, n (%) | 27 (84) | 19 (86) |
| Duration of follow up (days), median (IQR) | 491 (386,603) | 506 (390,648) |
| Ever smokers, n (%) | 10 (31) | 6 (27) |
| Aetiology, n (%) | Post-infectious: 16 (50) | Post-infectious: 13 (59) |
| Idiopathic: 11 (34) | Idiopathic: 5 (23) | |
| Rheumatological: 2 (6) | Rheumatological: 1 (4) | |
| Other: 3 (9) | Other: 3 (14) | |
| Bhalla score, mean (SD) | 12 (9) | 12 (9) |
| Number of lobes involved, median (IQR) | 3.5 (2,5) | 3.5 (2,5) |
| BSI score, median (IQR) | 8.5 (4,12.8) | 9 (4.5,11.3) |
| Severity (BSI classification), n (%) | Mild: 9 (28) | Mild: 6 (27) |
| Moderate: 8 (22) | Moderate: 4 (18) | |
| Severe: 15 (50) | Severe: 12 (55) | |
| Self-reported exacerbation frequency in previous year, median (IQR) | 3 (2,5.8) | 3 (2.3,6) |
| Asthma diagnosis, n (%) | 7 (22) | 6 (27) |
| Previous pseudomonas on sputum culture, n (%) | 7 (22) | 5 (23) |
| Previous hospitalisation, n (%) | 9 (28) | 8 (36) |
| Treatment details (all given as n (%)) | ||
| Short-acting inhaled bronchodilator | 13 (41) | 10 (45) |
| Long-acting inhaled bronchodilator | 12 (38) | 8 (36) |
| Inhaled corticosteroid use | 16 (50) | 11 (50) |
| Long term macrolide therapy, n (%) | 2 (6) | 2 (9) |
| Lung function measurements: (all given as mean (SD)) | ||
| FEV1(L), mean (SD) | 1.96 (0.90) | 2.02 (0.95) |
| FEV1% predicted (SD) | 78 (26) | 76 (28) |
| FEV1/FVC ratio, (SD) | 0.71 (0.15) | 0.71 (0.17) |
| Stable PEFR (L/min), (SD) | 334 (104) | 337 (110) |
| PEFR variability, % best (see text) | 12.4 (8.2) | 13.8 (9.4) |
| SGRQ and CAT scores (all given as mean (SD)) | ||
| Symptoms | 48.8 (24.3) | 50.2 (26.1) |
| Activity | 40.3 (27.8) | 41.8 (27.7) |
| Impact | 27.2 (16.5) | 29.4 (14.9) |
| Total SGRQ score | 34.8 (18.1) | 37.6 (16.9) |
| CAT score | 16.6 (7.0) | 17.2 (7.1) |