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. 2015 Feb 11;10(2):e0117993. doi: 10.1371/journal.pone.0117993

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© 2015 Bearoff et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — A composite female and male clinical disease course for all consomic strains (N≥149 per sex, N≥5 per strain) studied was generated using the mean daily clinical scores. The significance of the observed differences in disease course severity was determined by two-way ANOVA followed by Bonferroni multiple comparison test. A significant effect of sex (p<0.0001), days post-immunization (p<0.0001), and sex-by-days post-immunization interaction term (p<0.0001) were detected with * p<0.05; ** p<0.01; *** p<0.001; **** p<0.0001.