Table 3. Description of clusters containing 3 or more isolates in this study, and their worldwide distribution in the SITVIT2 database.
| SIT (Lineage) Octal Number Spoligotype Description | Number (%) in study | % in study vs. database | Distribution in Regions with ≥3% of a given SIT* | Distribution in countries with ≥3% of a given SIT** |
|---|---|---|---|---|
| 33 (LAM3) 776177607760771 | 11 (10.68) | 0,84 | AMER-S 34.96, AFRI-S 24.81, AMER-N 12.14, EURO-S 10.84, EURO-W 6.26, AMER-C 4.12 | ZAF 24.81, PER 16.95, USA 12.14, BRA 10.92, ESP 6.79, ARG 4.35, FXX 4.05, ITA 3.51, HND 3.28 |
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| 53 (T1) 777777777760771 | 9 (8.74) | 0,14 | EURO-W 15.0, AMER-S 14.35, AMER-N 12.93, EURO-S 9.02, EURO-N 7.17, ASIA-W 7.0, AFRI-S 4.76, AFRI-E 4.46, ASIA-E 4.09, AFRI-N 3.37, EURO-E 3.13, CARI 3.1, AMER-C 3.1 | USA 12.65, FXX 7.55, BRA 5.62, ITA 5.11, ZAF 4.65, PER 3.74, TUR 3.33, AUT 3.28 |
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| 50 (H3) 777777777720771 | 8 (7.77) | 0,2 | AMER-S 26.08, EURO-W 14.98, AMER-N 14.98, EURO-S 9.84, CARI 4.96, EURO-E 4.71, EURO-N 4.66, AFRI-N 3.63, AFRI-S 3.45, AFRI-M 3.22 | USA 14.96, PER 13.65, BRA 7.15, FXX 5.87, AUT 5.19, ITA 4.63, ESP 4.63, ZAF 3.45, CMR 3.17, CZE 3.12 |
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| 37 (T3) 777737777760771 | 7 (6.8) | 1,34 | AFRI-E 19.19, EURO-N 11.9, EURO-W 11.52, ASIA-W 10.56, AMER-S 9.21, AMER-N 8.64, ASIA-E 6.14, EURO-S 5.76, EURO-E 4.42, ASIA-S 3.65, AFRI-S 3.26 | ETH 16.7, USA 7.68, SWE 5.18, SAU 4.99, CHN 4.99, FXX 4.22, ITA 4.03, BRA 3.65, ZAF 3.26, DNK 3.26 |
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| 42 (LAM9) 777777607760771 | 7 (6.8) | 0,2 | AMER-S 31.16, AMER-N 11.33, EURO-S 10.81, EURO-W 9.04, AFRI-N 8.19, EURO-N 4.68, CARI 4.05, AMER-C 3.4, AFRI-E 3.4, AFRI-S 3.02 | BRA 13.07, USA 11.33, COL 7.28, MAR 6.73, ITA 6.25, FXX 4.82, PER 3.54, ESP 3.2, VEN 3.17, ZAF 3.02 |
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| 52 (T2) 777777777760731 | 3 (2.91) | 0,31 | EURO-W 18.95, ASIA-E 14.97, EURO-N 13.4, AMER-N 11.62, EURO-S 5.13, ASIA-W 5.13, AFRI-M 5.13, AFRI-E 4.82, EURO-E 4.19, AMER-C 3.35, AMER-S 3.04 | CHN 11.62, USA 11.2, SWE 9.42, FXX 8.69, BEL 4.71, CMR 4.19, ITA 3.35, JPN 3.14, ETH 3.14 |
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| 211 (LAM3) 776137607760771 | 3 (2.91) | 2,83 | AMER-N 30.19, AMER-C 20.76, EURO-W 19.81, AMER-S 18.87, EURO-S 7.55 | USA 30.19, MEX 20.76, FXX 18.87, BRA 11.32, ESP 4.72 |
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* Worldwide distribution is reported for regions with more than 3% of a given SITs as compared to their total number in the SITVIT2 database. The definition of macro-geographical regions and sub-regions (http://unstats.un.org/unsd/methods/m49/m49regin.htm) is according to the United Nations; Regions: AFRI (Africa), AMER (Americas), ASIA (Asia), EURO (Europe), and OCE (Oceania), subdivided in: E (Eastern), M (Middle), C (Central), N (Northern), S (Southern), SE (South-Eastern), and W (Western). Furthermore, CARIB (Caribbean) belongs to Americas, while Oceania is subdivided in 4 sub-regions, AUST (Australasia), MEL (Melanesia), MIC (Micronesia), and POLY (Polynesia). Note that in our classification scheme, Russia has been attributed a new sub-region by itself (Northern Asia) instead of including it among rest of the Eastern Europe. It reflects its geographical localization as well as due to the similarity of specific TB genotypes circulating in Russia (a majority of Beijing genotypes) with those prevalent in Central, Eastern and South-Eastern Asia.
** The 3 letter country codes are according to http://en.wikipedia.org/wiki/ISO_3166-1_alpha-3; countrywide distribution is only shown for SITs with ≥3% of a given SITs as compared to their total number in the SITVIT2 database. Note that FXX code designates Metropolitan France.