Table 1.
Contribution | Phenotypes | Genotypes | Covariates | Medication | Longitudinal | Variants | Scope |
---|---|---|---|---|---|---|---|
Balliu et al. [2014] | DBP | dose, geno | Age, smoke | unadjusted | longitudinal | all | Chromosome 3 with excess IBD |
Chen et al. [2014] | rSBP, DBP | dose | Age, sex, smoke | excluded | baseline: first non-missing | MAF < 5% | genome |
Hailine et al. [2014] | HTN | dose | None | unadjusted | any(HTN) | all | genome |
He and Pitkäniemi [2014] | log(SBP) | dose | Age | unadjusted | max(SBP) | MAF < 1% | genome |
Lacey et al. [2014] | SBP | dose, gwas | Age, sex, smoke | excluded | baseline: time1 | MAF > 1% | genome |
Li et al. [2014] | SBP | dose | Age, sex | unadjusted | baseline: first non-missing | all | genome |
Liu et al. [2014] | HTN | dose | Age, smoke | adjusted | longitudinal | all | Chromosome 3 |
Malzahn et al. [2014] | rSBP | dose, gwas | Age, sex, age×sex | excluded | baseline: time1 | all | Five genes on Chromosome 3 |
Zhang and Pan [2014] | HTN, SBP | geno | Age, sex, smoke | unadjusted | baseline: time1 | MAF > 5% | 6,228 common variants |
DBP, diastolic blood pressure; HTN, hypertension; IBD, identity-by-descent; MAF, minor allele frequency; rSBP, rank-transformed SBP; SBP, systolic blood pressure.