Table 3.
Sex hormones serum levels in patients with VKC in remission phase compared to healthy subjects.
| Late puberty | ||
|---|---|---|
| VKC | Healthy | |
| N | 6 | 12 |
| Age | ||
| Mean ± SD | 14–17 | 14–17 |
| Range | 15.3 ± 1 | 15.7 ± 1 |
| LH (mUI/mL) | ||
| Mean ± SD | 2.7 ± 0.6 | 2.6 ± 1.4 |
| Range | 2.1–3.5 | 1.1–5.4 |
| FSH (mUI/mL) | ||
| Mean ± SD | 5.8 ± 3.8 | 5.2 ± 1.5 |
| Range | 1.4–8.2 | 2.9–9.8 |
| Total testosterone (ng/100 mL) | ||
| Mean ± SD | 369 ± 142 | 369 ± 142 |
| Range | 202–593 | 254–789 |
| Free testosterone (ng/100 mL) | ||
| Mean ± SD | 17.1 ± 42* | 24.8 ± 6.6 |
| Range | 202–593 | 254–789 |
| DHT (pg/mL) | ||
| Mean ± SD | 362 ± 37 | 445 ± 89 |
| Range | 320–386 | 289–593 |
| Estradiol (pg/mL) | ||
| Mean ± SD | 21 ± 9 | 27 ± 7 |
| Range | 15–37 | 19–41 |
| Estrone (pg/mL) | ||
| Mean ± SD | 36.5 ± 7* | 25.5 ± 2.7 |
| Range | 27–43 | 22–30 |
| DHEAS (ng/mL) | ||
| Mean ± SD | 1131 ± 700* | 1783 ± 398 |
| Range | 645–2370 | 1047–2648 |
| D4A (ng/mL) | ||
| Mean ± SD | 1.4 ± 0.5 | 1.6 ± 0.3 |
| Range | 1–2.2 | 1.1–2.1 |
| Cortisol (ng/mL) | ||
| Mean ± SD | 130 ± 63 | 119 ± 37 |
| Range | 56–209 | 76–203 |
| SHBG (nmol/L) | ||
| Mean ± SD | 73 ± 44* | 30 ± 9 |
| Range | 36–123 | 13–39 |
VKC: vernal keratoconjunctivitis; * P < 0.05; N: number; SD: standard deviation; LH: luteinizing hormone; FSH: follicle-stimulating hormone; DHT: dihydrotestosterone; DHEAS: dehydroepiandrosterone-sulfate; D4A: delta-4-androstenedione; SHBG: sex hormones binding globulin.