TABLE 4.
Protein expression differences between WT (26695) and the Δhp119 mutant strain under oxygen stressa
| TIGR ORF | Protein identification | Fold change (mean) | SD |
|---|---|---|---|
| HP1195 | Elongation factor, EF-G, isoform 1 | −1.75 | 0.16 |
| HP0109 | Molecular chaperone, DnaK, isoform 1 | −3.03 | 0.25 |
| HP0072 | Urease subunit B, UreB, isoform 1 | −3.32 | 0.43 |
| HP0072 | Urease subunit B, UreB, isoform 2 | −2.47 | 0.86 |
| HP0010 | Molecular chaperone, GroEL, isoform 1 | −3.15 | 0.04 |
| HP0010 | Molecular chaperone, GroEL, isoform 2 | −2.40 | 0.13 |
| HP0840 | Flagellin subunit A, FlaA | −13.82 | 4.28 |
| HP0795 | Trigger factor | −5.55 | 2.07 |
| HP1293 | RNA polymerase, RpoA, isoform 1 | −1.88 | 0.18 |
| HP1555 | Elongation factor, EF-Ts | −5.89 | 0.67 |
| HP0310 | Peptidoglycan deacetylase, PgdA, isoform 1 | −66.30 | 8.20 |
| HP0170 | Hypothetical protein | −20.38 | 2.46 |
| HP0825 | Thioredoxin reductase, TrxR isoform 1 | −3.37 | 0.29 |
| HP0068 | Urease subunit G, UreG | −3.47 | 0.38 |
| HP0691 | 3-Oxoadipate coenzyme A-transferase subunit A | −8.24 | 1.25 |
| HP0389 | Superoxide dismutase, SodB | −5.96 | 1.04 |
| HP0390 | Thiol peroxidase, TagD (Tpx) | −19.40 | 6.32 |
| HP0243 | Neutrophil-activating protein, NapA isoform 1 | −9.23 | 2.46 |
| HP0322 | Poly-E-rich protein | +7.32 | 1.07 |
| HP1195 | Elongation factor, EF-G, isoform 2 | +1.86 | 0.06 |
| HP0109 | Molecular chaperone, DnaK, isoform 2 | +5.24 | 0.38 |
| HP0010 | Molecular chaperone, GroEL, isoform 3 | +14.14 | 7.11 |
| HP0828 | ATP synthase F0F1 subunit A, AtpA | +30.8 | 4.60 |
| HP0512 | Glutamine synthase, GlnA | +2.11 | 0.02 |
| HP1205 | Elongation factor, EF-Tu | +2.17 | 0.45 |
| HP0310 | Peptidoglycan deacetylase, PgdA, isoform 2 | +2.10 | 0.07 |
| HP0154 | Enolace | +2.68 | 0.25 |
| HP1293 | RNA polymerase, RpoA, isoform 2 | +18.49 | 9.82 |
| HP1563 | Alkyl hydroperoxide reductase, AhpC | +4.91 | 0.59 |
| HP0825 | Thioredoxin reductase, TrxR, isoform 2 | +3.92 | 0.56 |
| HP1588 | Hypothetical protein | +4.26 | 0.59 |
| HP0697 | Hypothetical protein | +34.70 | 5.46 |
| HP0243 | Neutrophil-activating protein, NapA isoform 2 | +5.43 | 0.20 |
a
TIGR ORF (open reading frame) number refers to H. pylori 26695 genome sequence. Fold change represents the density of each protein spot derived from Δhp119 mutant (red) in comparison to that from the WT (green). Data are means from two independent experiments with standard deviations.