FIG 7.

Comparison of the structures of the sixth adenylation domains of GLNRPS4 and EcdA, generated via homology modeling using SWISS-MODEL, with the RSCB PDB ID 1AMU structure as the template. (A) Three-dimensional structures of adenylation domains from GLNRPS4 and EcdA. (B) Top-down views of the modeled substrate-binding pockets. (C) Side-on views generated by rotating the structures 90° around the horizontal plane. Residues are colored and labeled according to their positions in the 10-amino-acid specificity code. Amino acids at position 1 and position 10 are shown in red and blue, respectively, whereas the amino acids in the rest of the positions are shown in yellow.