Figure 5. IFNβ restricts viral replication in MEF but not primary neurons.
Primary hippocampal neurons or MEF were treated with 100U/mL recombinant IFNβ or vehicle control and infected with LCMV (MOI=1) (A) or MV-Edmonston (MOI=1) (B). RNA was collected at 24 and 48 h post-infection and viral replication was detected by qRT-PCR. Relative gene expression level represents pooling of data from independent experiments after normalization within a given experiment. Results are representative of 3 independent experiments. **p<0.01.