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Overview of the Inter-species Pathway Perturbation Prediction Challenge. Participants were asked to predict the perturbation state of pathways in human cells (outlined in red) given corresponding data in rat. The organizers used a 25% cutoff on FDR to classify a pathway as significantly enriched in differentially expressed genes, based on the GSEA. Challengers were asked to give a confidence level that the GSEA FDR values on the test data (see red box) will be <0.25 for each stimuli
