Table 2.

Associations of overall mean systolic blood pressure (average from study entry to time of neuroimaging) with prevalence of white matter hyperintensity greater than or equal to the median and with mean fractional anisotropy in each tract of interest

White matter hyperintensity greater than or equal to the median
	Uncinate tract, left	Uncinate tract, right	Superior longitudinal fasciculus, left	Superior longitudinal fasciculus, right	Cingulum, left	Cingulum, right
Mean difference, mm Hg (95% CI)	5.2 (2.2 to 8.2)	3.5 (0.5 to 6.6)	5.1 (2.1 to 8.1)	5.8 (2.8 to 8.8)	3.2 (−0.5 to 6.8)	−0.7 (−5.1 to 3.7)
Adjusted P value	0.001	0.04	0.001	0.001	0.07	0.99
Fractional anisotropy
	Uncinate tract, left	Uncinate tract, right	Superior longitudinal fasciculus, left	Superior longitudinal fasciculus, right	Cingulum, left	Cingulum, right
Correlation coefficient	−0.142	−0.157	−0.172	−0.142	−0.182	−0.166
Adjusted P value	0.03	0.01	0.007	0.04	0.05	0.05

P values are from logistic regressions with presence of white matter hyperintensity as the dependent variable and from linear regression with fractional anisotrophy as dependent variable, adjusted for age, stroke, and antihypertensive medication use.

Abbreviation: CI, confidence interval.