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Effects of MMP-3 treatment on SCp2 mouse mammary epithelial cells cultured at different cell densities. Either 50K (top row), 100K (middle row), or 250K (bottom row) SCp2 cells were plated in 35-mm plates, and then treated as controls (left column) or with MMP-3 (middle column). Cell area measurements indicate significantly increased cell spreading with MMP-3 treatment at all three densities (right column). Scale bars, 250 μm in large views and 50 μm in insets.
