TABLE 2.
HA receptor binding preferences of wild-type and rescued viruses
| Virus | Residue at HA 226/228 | Titer for receptor(s)a : |
||
|---|---|---|---|---|
| α-2,3 + α-2,6 | α-2,6 | α-2,3 | ||
| KS-83533N | V/S | 64 | 64 | 0 |
| KS-91088 | V/S | 128 | 128 | 0 |
| KS-110529 | V/S | 128 | 64 | 0 |
| KS-107824 | V/G | 64 | 32 | 4 |
| rgKS-107824 | V/G | 64 | 32 | 8 |
| rgKS-107824-G228S | V/S | 256 | 256 | 0 |
| A/chicken/Jena/4836/1983 (H2N2) | Q/G | 256 | 0 | 128 |
| A/Brisbane/59/2007 (H1N1) | −b | 512 | 512 | 0 |
a
The titer shown is the reciprocal of the highest virus dilution that hemagglutinated RBCs bearing various sialic acid receptors.
b
−, not applicable.