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Expression levels of proinflammatory cytokines in response to LPS or HAd5. mRNA expression levels of IFN-β (A), IL-1β (B), IL-8 (C), and IP-10 (D) of THP-1-derived DCs challenged with 10 ng/ml LPS or 20,000 pp/cell HAd5, FX-HAd5, IC-HAd5, or FX-IC-HAd5 were measured at 3 and 6 h. TAK-242 was used to inhibit TLR4 signaling where indicated.
