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VSVΔG-H5N1 is nonpathogenic in mice. Groups of five 6- to 8-week-old female BALB/c mice were lightly anesthetized prior to i.n. vaccination with either 1.25 × 107 PFU of VSVΔG-H5N1 or 106 PFU of a VSV recombinant expressing EGFP. Weights were recorded daily for 13 days postinoculation and are graphically displayed as the average percentage of the prevaccination weight. Error bars represent 1 standard deviation above and below the average weight.
