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HPV E7 inhibits myoblast differentiation. C2C12 cells were transduced with retroviruses encoding SV40 ST, PyV ST, HPV16 E6, HPV16 E7, and HPV16 E7 ΔPTHLE and ΔDLYC mutants or with an empty vector retrovirus, or they were mock transduced. The extent of differentiation was measured visually (A) or by blotting for MHC (B) 7 days after the initiation of differentiation.
