TABLE 2.
Corneal scarring of BALB/c and C57BL/6 mice after ocular infection with gK recombinant virusesa
| Virus | CS after virus infection at various doses (PFU/eye) |
||||
|---|---|---|---|---|---|
| C57BL/6 mice |
BALB/c mice |
||||
| 2 × 106b | 2 × 105 | 2 × 104 | 2 × 103 | 2 × 102 | |
| NgK | 2.4 ± 0.7 | 0.7 ± 0.3 | 0 | 0 | 0 |
| MgK | 1.1 ± 0.4 | 0.7 ± 0.3 | 0.4 ± 0.4 | 0 | 0 |
| RgK | 0.6 ± 0.3 | 0.5 ± 0.2 | 1 ± 1 | 1.1 ± 0.6 | 0.1 ± 0.1 |
a
Mice were infected ocularly with the specified amount of each virus, and CS was determined 28 days after challenge. CS values are indicated as the means ± the standard deviations.
b
These values were significantly different from RgK but not for MgK as determined using the Student t test.