TABLE 4.
Known mutations in genes conferring resistance to colistin and corresponding variants in Chryseobacterium oranimense G311, C. gleum ATCC 35910, and Chryseobacterium sp. strain CF314 variants
| Gene | Known mutation (reference) | Organism | Mutation |
||
|---|---|---|---|---|---|
| C. oranimense G311 (EBI gene identifier no.) | C. gleum ATCC 35910 | Chryseobacterium sp. strain CF314 | |||
| pmrA | E8D (65) | Acinetobacter baumannii | E8D (CEJ70734) | E8D | E8D |
| G53S (62) | Enterobacter aerogenes | No mutation (CEJ70734) | No mutation | No mutation | |
| pmrB | L208F (64) | Acinetobacter baumannii | L208F (CEJ70733) | No mutation | No mutation |
| P360Q (64) | Acinetobacter baumannii | P360Q (CEJ70733) | No mutation | No mutation | |
| lpxA | G68D (65) | Acinetobacter baumannii | G68D (CEJ70978) | G68D | G68D |
| Q72K (65) | Acinetobacter baumannii | No mutation (CEJ70978) | No mutation | No mutation | |
| H159D (65) | Acinetobacter baumannii | No mutation (CEJ70978) | No mutation | No mutation | |
| Insertional inactivation (66) | Acinetobacter baumannii | No mutation (CEJ70978) | No mutation | No mutation | |
| lpxC | I38T (67) | E. coli | No mutation (CEJ70979) | No mutation | No mutation |
| P30L (66) | Acinetobacter baumannii | No mutation (CEJ70979) | No mutation | No mutation | |
| Insertional inactivation (66) | Acinetobacter baumannii | No mutation (CEJ70979) | No mutation | No mutation | |
| lpxD | M290A (68) | E. coli | No mutation (CEJ70980) | No mutation | No mutation |
| phoP | NDa | ||||
| phoQ | D179(L/A) (4) | E. coli | No mutation (CEJ67802) | No mutation | No mutation |
a
ND, not detected.