FIG 3.

Predictive blood (solid lines) and URT (broken lines) peramivir concentration-time curves for the following peramivir regimens: a 5-mg/kg dose every 12 h for 5 days (regimen 1) (top left panel), a 10-mg/kg dose every 24 h for 5 days (regimen 2) (top right panel), a 10-mg/kg dose every 12 h for 5 days (regimen 3) (bottom left panel), and a 20-mg/kg dose every 24 h for 5 days (regimen 4) (bottom right panel). Lines a, b, c, and d represent 300, 200, 100, and 50 nM, respectively. URT, upper respiratory tract.