TABLE 3.
Day after treatment | Peramivir IC50 (nM) fora: |
||
---|---|---|---|
H1N1 pdm09 | H3N2 | B | |
Day 0 (n = 2/6/7)b | 0.15 ± 0.02 (0.15, 0.14–0.17) | 0.18 ± 0.04 (0.20, 0.12–0.22) | 1.05 ± 0.27 (1.00, 0.72–1.49) |
Day 1 (n = 3/6/6) | 0.13 ± 0.05 (0.11, 0.10–0.19) | 0.20 ± 0.02 (0.20, 0.18–0.24) | 1.45 ± 0.43 (1.37, 0.97–1.22) |
Day 2 (n = 1/6/6) | 0.24 | 0.16 ± 0.02 (0.16, 0.13–0.20) | 1.09 ± 0.20 (1.02, 0.83–1.36) |
Day 3 (n = none/1/1) | None | 0.17 | 0.94 |
Day 4 (n = none/1/0) | None | 0.22 | None |
Day 5 (n = 1/0/3) | 0.10 | None | 1.04 ± 0.12 (0.99, 0.96–1.19) |
Data are mean ± SD (median, range).
Number of H1N1 pdm09/H3N2/B isolates.