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. 2015 Feb 11;59(3):1643–1649. doi: 10.1128/AAC.04263-14

TABLE 3.

Influenza virus susceptibility to peramivir

Day after treatment Peramivir IC50 (nM) fora:
H1N1 pdm09 H3N2 B
Day 0 (n = 2/6/7)b 0.15 ± 0.02 (0.15, 0.14–0.17) 0.18 ± 0.04 (0.20, 0.12–0.22) 1.05 ± 0.27 (1.00, 0.72–1.49)
Day 1 (n = 3/6/6) 0.13 ± 0.05 (0.11, 0.10–0.19) 0.20 ± 0.02 (0.20, 0.18–0.24) 1.45 ± 0.43 (1.37, 0.97–1.22)
Day 2 (n = 1/6/6) 0.24 0.16 ± 0.02 (0.16, 0.13–0.20) 1.09 ± 0.20 (1.02, 0.83–1.36)
Day 3 (n = none/1/1) None 0.17 0.94
Day 4 (n = none/1/0) None 0.22 None
Day 5 (n = 1/0/3) 0.10 None 1.04 ± 0.12 (0.99, 0.96–1.19)
a

Data are mean ± SD (median, range).

b

Number of H1N1 pdm09/H3N2/B isolates.