TABLE 1.
Clinical characteristics of AST-reviewed Gram-negative bloodstream infection cohort (n = 132)
| Clinical characteristica | Value |
|---|---|
| Age, yr, mean ± SD | 55 ± 16.3 |
| Male, no. (%) | 72 (55) |
| Comorbidities, no. (%) | |
| Diabetes mellitus | 12 (9) |
| Heart disease | 20 (15) |
| Lung disease | 7 (5) |
| Liver disease | 14 (11) |
| Kidney disease | 16 (12) |
| Vascular disease | 6 (5) |
| Stroke/TBI | 17 (13) |
| Malignancy | 30 (23) |
| BMT | 3 (2) |
| Solid-organ transplant | 15 (11) |
| HIV | 11 (8) |
| Allergy, no. (%) | 40 (30) |
| Beta-lactam | 22 (17) |
| Service, no. (%) | |
| Medicine | 32 (24) |
| Surgery | 35 (27) |
| Trauma | 20 (15) |
| MICU/SICU | 26 (20) |
| Cancer | 13 (10) |
| Otherb | 6 (5) |
| Location, no. (%) | |
| ED | 30 (23) |
| Med-Surg | 42 (32) |
| ICU | 36 (27) |
| Trauma | 19 (14) |
| Otherc | 5 (4) |
| ID consult, no. (%) | 109 (83) |
| Source of bacteremia, no. (%) | |
| Primary | 51 (39) |
| Catheter related | 12 (9) |
| Lung | 13 (10) |
| Urine | 34 (26) |
| Intra-abdominal | 10 (8) |
| VAD | 5 (4) |
| SSTI | 3 (2) |
| Otherd | 4 (3) |
| Type of acquisition, no. (%) | |
| Hospital acquired, >48 h | 78 (59) |
| Community acquired, <48 h | 54 (41) |
| Health care associatede | 30 (23) |
| Length of hospitalization, days, mean ± SD | 33.4 ± 46.5 |
| ICU stay, no. (%) | 78 (59) |
| Length of ICU stay, d, mean ± SD | 18.2 ± 38 |
| Inpatient mortality, no. (%) | 24 (18) |
a
Abbreviations: TBI, traumatic brain injury; HIV, human immunodeficiency virus; VAD, ventricular assist device; SSTI, skin and soft tissue infection; BMT, bone marrow transplant.
b
Neurology, pediatrics, and obstetrics.
c
BMT, pediatric ward, and postpartum ward.
d
Central nervous system, mediastinitis, and vascular graft.
e
Criteria: from another hospital or facility, hospitalization of <3 months, indwelling device (VAD, line), hemodialysis.