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(A) Bactericidal activities of VXc-486 and moxifloxacin (MXF) against Mycobacterium tuberculosis (Erdman strain). Representative results from two independent experiments cultured in triplicate are shown. Both VXc-486 and MXF were used at 4-fold MICs; VXc-486 was used at a concentration of 0.24 μg/ml and MXF was used at a concentration of 0.12 μg/ml. (B) Bactericidal activities of VXc-486, isoniazid (INH), and moxifloxacin (MXF) against Mycobacterium kansasii (strain 0008).
