Table 1.
Variables | Never-users | Ever-users | P | ||
---|---|---|---|---|---|
n | % | n | % | ||
n = 886418 | 783321 | 103097 | |||
Age (years) | |||||
<40 | 33874 | 4.32 | 3269 | 3.17 | <0.0001 |
40-49 | 102887 | 13.13 | 11623 | 11.27 | |
50-59 | 199819 | 25.51 | 27204 | 26.39 | |
60-69 | 200241 | 25.56 | 29608 | 28.72 | |
≥70 | 246500 | 31.47 | 31393 | 30.45 | |
Sex (men) | 399333 | 50.98 | 49282 | 47.80 | <0.0001 |
Diabetes duration (years) | |||||
<1 | 70381 | 8.98 | 1434 | 1.39 | <0.0001 |
1-3 | 133250 | 17.01 | 7184 | 6.97 | |
3-5 | 123610 | 15.78 | 11094 | 10.76 | |
≥5 | 456080 | 58.22 | 83385 | 80.88 | |
Hypertension | 443728 | 56.65 | 77740 | 75.40 | <0.0001 |
Chronic obstructive pulmonary disease | 114018 | 14.56 | 24177 | 23.45 | <0.0001 |
Cerebrovascular disease | 116947 | 14.93 | 25453 | 24.69 | <0.0001 |
Nephropathy | 93744 | 11.97 | 23717 | 23.00 | <0.0001 |
Ischemic heart disease | 174225 | 22.24 | 40511 | 39.29 | <0.0001 |
Peripheral arterial disease | 89324 | 11.40 | 24510 | 23.77 | <0.0001 |
Eye disease | 63803 | 8.15 | 21179 | 20.54 | <0.0001 |
Obesity | 11423 | 1.46 | 1961 | 1.90 | <0.0001 |
Dyslipidemia | 371714 | 47.45 | 69015 | 66.94 | <0.0001 |
Other cancer prior to baseline | 93619 | 11.95 | 13058 | 12.67 | <0.0001 |
Sulfonylurea | 577003 | 73.66 | 99140 | 96.16 | <0.0001 |
Metformin | 512063 | 65.37 | 96850 | 93.94 | <0.0001 |
Acarbose | 80640 | 10.29 | 38971 | 37.80 | <0.0001 |
Insulin | 102359 | 13.07 | 39119 | 37.94 | <0.0001 |