Table 1.

Timeline

Previous 6 weeks:	generalised malaise, anorexia, rapid weight loss, as well as epigastric pain and vomiting following meals
Day 1:	Admission to Accident and Emergency with collapse and coffee-ground vomit, transfer to Intensive Care Unit
Day 2 (02:00):	Continuous veno-venous haemofiltration instituted
Day 2 (14:00):	Doxorubicin (50mg, intravenous, once), rasburicase and Pabrinex® (vitamins thiamine, riboflavin, pyridoxine, ascorbic acid and nicotinamide) administered
Day 2 (15:00)	Plasma lactate peaks at 21.0mmol/L
Day 3 (20:00)	Plasma lactate plateaus at approximately 4mmol/L
Day 7:	Transferred to haematology
Day 15:	Surgical evacuation of haematoma
Day 16:	Transfer to Neurological Intensive Care Unit
Day 20:	Withdrawal of care in patient’s best interests
Day 21:	Patient dies, 02.17 a.m.