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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biochem J. 2015 Jan 1;465(1):63–78. doi: 10.1042/BJ20140923

Figure 11. Schematic representation of the role of F-loop of UNC-60A in inhibiting polymerization/nucleation.

Figure 11

An actin monomer is placed on the surface of UNC-60A/G-actin model, the F-loop of UNC-60A gets in close proximity with the helix (T203-K215) of subdomain 4 of actin (yellow), which interacts with the helix (I287-L293) of subdomain 3 of adjacent protomer (blue) in co-filament structure of ADF and F-actin.