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Immunohistochemical staining demonstrates distinct patterns of Toca vector localization after intracranial and intravenous delivery in a Tu-2449 mouse brain tumor model. (a) Toca GFP detected with rabbit anti-GFP antibody; (b) Toca 511 detected with mouse anti-CD antibody. Coronal sections shown; original magnification, ×20. Center: Tumor interior. Right: Tumor periphery.
