Table 1.

Toca 511 DNA PCR Signal in Blood from B6C3F1 Mice over Time

Blood						Distribution
Group	Treatment	Cohort	n	No. positive	Range of positivity (copies/μg)	Low	Medium	High
1	B6C3F1 Control	30	15	0	0–0	0	0	0
		90	15	0	0–0	0	0	0
		120	15	0	0–0	0	0	0
		150	15	0	0–0	0	0	0
		180	5	0	0–0	0	0	0
2	B6C3F1 Toca 511 107 IV	30	20	20	2,030–49,779	9	11	0
		90	20	20	167–23,096	18	2	0
		120	19	18	576–9,753	18	0	0
		150	19	18	259–11,459	18	0	0
		180	20	20	199–14,823	20	0	0

IV, intravenous.