Table 1.
History of Neurologic Disorders Among Cases With BP and Controls
| Neurologic Disorder | Controlsa (n=261) |
Casesa (n=87) |
OR (95% CI)b |
P Value |
|---|---|---|---|---|
| Dementia | 4 (2) | 9 (10) | 6.75 (2.08–21.92) | .002 |
| Parkinson disease | 1 (<1) | 3 (3) | 9.00 (0.94–86.52) | .06 |
| MS | 1 (<1) | 1 (1) | 3.00 (0.19–47.96) | .44 |
| Cerebrovascular disease | 5 (2) | 5 (6) | 3.00 (0.87–10.36) | .08 |
| Seizures | 0 | 3 (3) | 11.54 (1.24– infinity)c | .01 |
| Any of the above | 11 (4) | 20 (23) | 6.85 (3.00–15.64) | <.001 |
| Dementia or Parkinson disease | 5 (2) | 12 (14) | 8.55 (2.75–26.63) | <.001 |
| Dementia, Parkinson disease, or MS | 6 (2) | 13 (15) | 7.45 (2.65–20.97) | <.001 |
| Dementia, Parkinson disease, MS, or cerebrovascular disease | 11 (4) | 17 (20) | 5.74 (2.46–13.40) | <.001 |
Abbreviations: BP, bullous pemphigoid; MS, multiple sclerosis; OR, odds ratio.
a
Values are No. of patients (%).
b
Odds of a history of the neurologic disorder among BP cases compared with matched controls.
c
OR, 95% CI, and P value estimated using exact conditional logistic regression.