Table 2.
History of Neurologic Disorders Among Cases With Generalized BP and Controls
| Neurologic Disorder | Controlsa (n=219) |
Casesa (n=73) |
OR (95% CI)b |
P Value |
|---|---|---|---|---|
| Dementia | 3 (1) | 9 (12) | 9.00 (2.44–33.24) | .001 |
| Parkinson disease | 0 | 2 (3) | 7.24 (0.56-infinity)c | .13 |
| MS | 1 (<1) | 1 (1) | 3.00 (0.19–47.96) | .44 |
| Cerebrovascular disease | 5 (2) | 3 (4) | 1.80 (0.43–7.53) | .42 |
| Seizures | 0 | 3 (4) | 11.54 (1.24-infinity)c | .03 |
| Any of the above | 9 (4) | 17 (23) | 6.79 (2.80–16.45) | <.001 |
| Dementia or Parkinson disease | 3 (1) | 11 (15) | 11.00 (3.07–39.43) | <.001 |
| Dementia, Parkinson disease, or MS | 4 (2) | 12 (16) | 9.00 (2.90–27.91) | <.001 |
| Dementia, Parkinson disease, MS, or cerebrovascular disease | 9 (4) | 14 (19) | 5.52 (2.21–13.76) | <.001 |
Abbreviations: BP, bullous pemphigoid; MS, multiple sclerosis; OR, odds ratio.
a
Values are No. of patients (%).
b
Odds of a history of neurologic disorder among generalized BP cases compared with matched controls.
c
OR, 95% CI, and P value estimated using exact conditional logistic regression.