Fig 2. The collagen homologous peptide, R1R2, decreases vascular remodeling in the carotid artery.
(A) Representative photomicrographs of the left carotid artery 14 days after ligation. Lumen (L), neointima (I) and media (M) in ligated vessels are shown. C indicates blood clot. Bar, 200 μm. Morphometric analyses of the lumen (B), intima+media (C), the external elastic lamina compartment (EEL; D), and intima/media ratio (E) 7 and 14 days after ligation. * indicates p<0.05, ** p< 0.01 and *** p< 0.001.