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. 2015 Feb 21;21(7):2080–2088. doi: 10.3748/wjg.v21.i7.2080

Table 2.

Serum levels of soluble heparin-binding epidermal growth factor-like growth factor and carcinoembryonic antigen according to disease groups

Groups Control2 (n = 60) High-risk3 (n = 30) EGC (n = 37) AGC (n = 30) P value4
Serum sHB-EGF1 (pg/mL) 94.7 ± 83.6 98.7 ± 67.3 165.3 ± 123.2 314.4 ± 127.5 < 0.001
Serum CEA1 (ng/mL) 1.8 ± 1.5 2.2 ± 1.1 2.4 ± 1.4 4.5 ± 5.1 0.001
1

All tested values are expressed as the mean ± standard deviation.

2

Control group includes individuals with normal mucosa or patients with simple chronic superficial gastritis and chronic atrophic gastritis.

3

High-risk group included patients with intestinal metaplasia and dysplasia.

4

One-way analysis of variance (ANOVA) test with the multiple comparisons by the post-hoc Bonferroni method is applied to compare the differences in means among disease groups. P < 0.05 (two-tailed) was considered statistically significant. AGC: Advanced gastric cancer; EGC: Early gastric cancer; CEA: Carcinoembryonic antigen; sHB-EGF: Soluble heparin-binding EGF-like growth factor.