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. 2015 Feb 21;21(7):2124–2130. doi: 10.3748/wjg.v21.i7.2124

Table 1.

Characteristics of patients with colorectal liver metastases n (%)

Variable Primary hepatectomy (n = 406) Secondary hepatectomy (n = 55) P value1
Sex (M/F) 266:140 36:19 0.99
Median age (yr) (range) 59.5 (26-80) 58 (36-80) 0.95
Number of CRLM (median, range) 1 (1-8) 1 (1-4) 0.01
CRLM size (median, range) 2.4 (0.2-7.5) 2.4 (1.0-7.5) 0.85
Liver metastases
Synchronous 279 (69) 39 (71) 0.74
Metachronous 127 (31) 16 (29)
CRLM number
Single 232 (57) 41 (75) 0.014
Multiple 174 (43) 14 (25)
CRLM treatment
Resection 324 (80) 25 (45) < 0.001
RFA 57 (14) 29 (53)
Both 25 (6) 1 (2)
T stage
T1 T2 T3 364 (90) 47 (85) 0.35
T4 42 (10) 8 (15)
N stage
N0 117 (29) 13 (24) 0.42
N1 or N2 289 (71) 42 (76)
Histological differentiation2
High grade 367 (90) 53 (96) 0.21
Low grade 39 (10) 2 (4)
Lymphatic invasion
(-) 172 (42) 16 (29) 0.02
(+) 129 (32) 26 (47)
Vascular invasion
(-) 168 (41) 29 (53) 0.14
(+) 102 (25) 10 (18)
Perineural invasion
(-) 191 (47) 20 (36) 0.38
(+) 74 (18) 11 (22)
Chemotherapy
Yes 373 (92) 50 (91) 0.79
No 33 (8) 5 (9)
1

χ2 test, Fisher’s exact test, or Mann Whitney U test;

2

High grade: well or moderately differentiated, Low grade: poorly differentiated or mucinous carcinoma. CRLM: Colorectal liver metastases.