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Clinical and biological response to eculizumab therapy. The figure shows data indicating neurological and renal improvement after administration of monoclonal C5 antibody eculizumab in our case with TA-TMA posthematopoietic progenitor cell transplantation with central nervous syprogenitor involvement. LDH levels were decreased dramatically, but thrombocyte count did not improve, possibly related to delayed hematopoietic engraftment.
