Table 3. Clinical data of second-line patients.
| Pat Id | Smoking status / pack years | Histology | Stage (UICC/AJCC) | Responder/ non-responder |
|---|---|---|---|---|
| UKH 001 | never | Adenocarcinoma | IV | Responder |
| UKH 002 | yes / 6 | Squamous cell carcinoma | IV | Responder |
| UKH 010 | ex-smoker / 30 | Adenocarcinoma | IV | non-responder |
| UKH 020 | ex-smoker / 35 | Squamous cell carcinoma | IV | non-responder |
| UKH 037 | yes / 34 | Adenocarcinoma | IV | non-responder |
In this group were four male and one female patients. The only female patient in this group (UKH 001) did respond to therapy. The median age of this patient group is 64 years. Patient UKH 010 demonstrated an EGFR mutation and was treated with TKI.